Real Madrid was held to a 0-0 draw by Getafe in the Spanish league on Thursday, putting it in danger of finishing outside of the top two in consecutive seasons for the first time in 45 years.
Manchester City kept the destination of the Premier League title in its own hands by beating Manchester United 2-0 on Wednesday to climb back above Liverpool with three games left this season.
A pair of Australian teams earned draws in the Asian Champions League on Tuesday, good enough to keep one alive in the competition while eliminating the other.
Melbourne Victory became the first team to be eliminated from the group stage despite its 1-1 draw against two-time champion Guangzhou Evergrande.
Kawasaki Frontale blew an early lead and drew 2-2 with visiting South Korean side Ulsan Hyundai in the Asian Champions League group H on Tuesday night at Todoroki Stadium.
Pirates reliever Nick Burdi left in tears with a right arm injury, a chilling low point for Pittsburgh in a 12-4 loss to the Arizona Diamondbacks on Monday night.
Carlos Vela scored two goals, Mark-Anthony Kaye had three assists and Los Angeles FC beat Seattle 4-1 on Sunday to hand the Sounders' their first loss of the season.
Three minutes into stoppage time, Manchester City forward Raheem Sterling slid across the field and puffed his chest to the crowd, roaring in elation. Tottenham players collapsed to the turf, some flat on their backs, forlorn and heartbroken.
Fernando Llorente sent Tottenham into its first European Cup semifinal in 57 years and ended Manchester City's quadruple hopes by scoring the decider in a breathtaking Champions League game that produced seven goals and saw an apparent injury-time winner for City ruled out after a video review.
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